Description
The product is a fully human anti-CD38 antibody that exhibits specificity for CD38. The release of soluble protein and the ability to internalize membrane-bound proteins indicate extracellular and intracellular functions of the protein. Diseases associated with CD38 include prolymphocytic leukemia and chronic lymphocytic leukemia 2.
Target
CD38
Target Alias Names
CD38 Molecule, ADP-Ribosyl Cyclase 1, 2-Phospho-Cyclic-ADP-Ribose Transferase, Cyclic ADP-Ribose Hydrolase 1, 2-Phospho-ADP-Ribosyl Cyclase, NAD(+) Nucleosidase, CD38 Antigen (P45), ADPRC 1, 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase, Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression