Description
The antibody is a chimeric (Mouse/Human) IgG antibody that binds to human B7-H3. The antibody exhibits in vivo activity against NCI-H1703 non-small cell lung cancer tumor cells when administered at a dose of 10 mg/kg.
Target
CD276
Target Alias Names
CD276 Molecule, CD276 Antigen, Costimulatory Molecule, B7 Homolog 3, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Isotype/Mimetic
Chimeric (Mouse/Human) IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression