Description
This is a recombinant humanized IgG antibody that specifically targets human B7-H3. It also cross-reacts with cynomolgus monkey. The antibody demonstrates an affinity of 62.9 nM towards human B7-H3 protein and an affinity of 592.3 nM towards cynomolgus monkey B7-H3 protein.
Target
CD276
Target Alias Names
CD276 Molecule, CD276 Antigen, Costimulatory Molecule, B7 Homolog 3, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression