Description
This HPAB-0241-CN product is a recombinant chimeric (mouse/human) IgG1, κappa antibody targeting human B7-H3, with an affinity of 7.3E-10 M. The antibody also has ADCC and ADCP activity against NCI-H322 cells.
Target
CD276
Target Alias Names
CD276 Molecule, Costimulatory Molecule, CD276 Antigen, B7 Homolog 3, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression