Description
This antibody was derived from a screening to obtain the anti-human PD-L1 humanized monoclonal antibody with a favorable specificity, affinity, and stability. The antibody can be specifically combined with human PD-L1, not combined with other B7 family members. It could activate T cells and inhibit tumor growth.
Target
CD274
Target Alias Names
CD274 Molecule, CD274 Antigen, B7 Homolog 1, Programmed Cell Death 1 Ligand 1, PDCD1 Ligand 1, PDCD1LG1, PDCD1L1
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression