Description
Recombinant Human Antibody (OX108) is capable of binding to CD200R, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CD200R mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CD200R mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
CD200R1
Target Alias Names
CD200R1, CD200 receptor 1, OX2R, MOX2R, CD200R, HCRTR2, cell surface glycoprotein CD200 receptor 1, MOX2 receptor, CD200 cell surface glycoprotein receptor, cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200
Isotypes/Mimetics
Human IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression