Description
Recombinant Human Antibody clone chAb-1, which is specific to Basigin. Recombinant chimeric antibody (Ab-1) binds to basigin and inhibited the PfRH5-basigin interaction and potently blocked erythrocyte invasion by all parasite strains tested.
Target
BSG
Target Alias Names
Basigin (Ok Blood Group), Tumor Cell-Derived Collagenase Stimulatory Factor, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Collagenase Stimulatory Factor, OK Blood Group Antigen, CD147 Antigen, EMMPRIN, TCSF, 5F7, Ok Blood Group, Basigin, CD147, M6, OK
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression