Description
Recombinant Human Antibody (AbD1556) is capable of binding to BMPR-IA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-BMPR-IA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-BMPR-IA proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
BMPR1A
Target Alias Names
BMPR1A, bone morphogenetic protein receptor, type IA, ALK3, SKR5, CD292, ACVRLK3, 10q23del, bone morphogenetic protein receptor type-1A, ALK-3, BMPR-1A, BMP type-1A receptor, activin receptor-like kinase 3, activin A receptor, type II-like kinase 3, serinethreonine-protein kinase receptor R5
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression