Description
This product is a recombinant human anti-idiotypic monoclonal antibody (IgG1, λ) that recognizes the variable region of murine mAb 14G2a. Mab 4B5 mimics the GD2 antigen and is capable of eliciting both a humoral and cellular anti-GD2 immune response. This antibody could be potentially used as a human anti-Id vaccine in patients with malignant melanoma. When administered to an individual, mAb 4B5 is effective in diagnosing, and/or treating neoplasias.
Target
Anti-GD2mAb 14G2a
Target Alias Names
Anti-GD2mAb 14G2a, Anti-GD2mAb, Anti-GD2 mAb, mAb 14G2a, 4B5, MAb 4B5, NovoVac-M1
Isotypes/Mimetics
Human IgG1, λ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression