Description
Antibody Malimo is an isolated monoclonal antibody that specifically binds to an extracellular epitope on the N-terminal half of BSEP and modulates BSEP function. Antibody Malimo recognizes an epitope present on the C-terminal half of BSEP.
Target
ABCB11
Target Alias Names
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11, Progressive Familial Intrahepatic Cholestasis 2, ATP-Binding Cassette Sub-Family B Member 11, BSEP, ABC Member 16, MDR/TAP Subfamily, Bile Salt Export Pump, Sister P-Glycoprotein, MDR/TAP Subfamily, ABC Member 16, EC 3.6.3.44, EC 3.6.3, PFIC-2, ABC16, BRIC2, PFIC2, PGY4, SPGP
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression