Description
Recombinant monoclonal antibody to CD40L. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma hu5c8 (Ruplizumab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
CD40L
Target Alias Names
CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression