Antibodies under a microscope

Ab03992-3.3

hRS7 (Sacituzumab)

Description

Recombinant monoclonal antibody to TROP2. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody hRS7 (Sacituzumab). This is a reformatted mouse IgG2b Fc SilentЩ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Target

TROP2

Target Alias Names

EGP-1, TACSTD2, GA733-1, M1S1, TROP-2, Tumor-associated calcium signal transducer 2, epithelial glycoprotein-1 antigen, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, IMMU-132, RS7, RS7-3G11

Isotype/Mimetic

IgG2b

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression