Description
Histone H3 (K36M Mutant Specific) (E8N1L) Rabbit mAb recognizes endogenous levels of K36M mutant histone H3.1, H3.2, and H3.3 proteins. The antibody may show slight cross-reactivity with wild-type histone H3.1, 3.2, or 3.3 when used at a high concentration. Careful titration of this antibody may be required to obtain optimal specificity. This antibody may detect a band of unknown origin at 50 kDa. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to K36M mutant sequence of human histone H3.3 protein.
Target
H3F3A (Lys36Met) mutation
Target Alias Names
H3-3A, H3F3A
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation