Description
Gasdermin D (E8G3F) Rabbit mAb recognizes endogenous levels of total Gasdermin D protein. This antibody recognizes the 30 kDa amino terminal fragment produced during pyroptosis by caspase-1, a 43 kDa fragment produced by caspase-3, as well as a 21 kDa fragment produced by cleavage at both sites. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Trp130 of human Gasdermin D protein.
Target
gasdermin D
Target Alias Name
GSDMD
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation