Description
DNMT3A (D23G1) Rabbit mAb detects endogenous levels of total DNMT3A protein. The antibody does not detect DNMT3A isoform 2 (Q9Y6K1-2/ NP_715640.2 or NP_001307822.1). In addition, this antibody does not cross-react with DNMT3B or other DNMT proteins. Focal cytoplasmic staining was observed in some tissues tested, testis in particular. Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Lys96 of human DNMT3A protein.
Target
DNMT3A
Target Alias Name
DNMT3A
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation