Description
Di-Methyl-Histone H3 (Lys79) (D15E8) XP® Rabbit mAb detects endogenous levels of histone H3 only when di-methylated on Lys79. The antibody does not cross-react with non-methylated, mono-methylated or tri-methylated Lys79. In addition, the antibody does not cross-react with methylated histone H3 Lys4, Lys9, Lys27, Lys36 or methylated histone H4 Lys20. Monoclonal antibody is produced by immunizing animals with a synthetic peptide containing histone H3 di-methyl lysine 79.
Target
H3 (Lys79) dimethylate
Target Alias Names
H3C1, H3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation