Description
Di-Methyl-Histone H3 (Lys36) (C75H12) Rabbit mAb (BSA and Azide Free) detects endogenous levels of histone H3.1, histone H3.2, and histone H3.3, only when di-methylated on Lys36. The antibody does not cross-react with non-methylated, mono-methylated, or tri-methylated Lys36. In addition, the antibody does not cross-react with di-methylated histone H3 Lys4, Lys9, Lys27, Lys79 or di-methylated histone H4 Lys20. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys36 is di-methylated.
Target
H3 (Lys36) dimethylate
Target Alias Names
H3C1, H3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression