Description
Cleaved TGF-β1 (Ala279)/ TGF-β3 (Ala301) (E5L1D) Rabbit mAb recognizes endogenous levels of TGF-β1 and TGF-β3 proteins only when cleaved at Ala279 and Ala301, respectively. This antibody does not cross-react with full-length TGF-β1, TGF-β2, or TGF-β3, nor does it react with cleaved TGF-β2. Upper bands present in human platelet and K-562 lanes are non-specific. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues adjacent to Ala279 and Ala301 of human TGF-β1 and TGF-β3 proteins, respectively.
Targets
TGFB2 (Ala303) cleaved, TGFB1 (Ala279) cleaved, TGFB3 (Ala301) cleaved
Target Alias Names
TGFB2, TGFB1, TGFB3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation