Description
Cleaved SARS-CoV-2 Spike Protein (Ser686) (E1W4P) Rabbit mAb recognizes SARS-CoV-2 spike protein only when cleaved at the S1/S2 cleavage site to produce the S2 subunit. Based on sequence analyses, this antibody is not predicted to cross-react with coronavirus spike proteins of SARS or MERS. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to N-terminal residues surrounding Ser686 of SARS-CoV-2 spike protein at the S1/S2 cleavage site.
Targets
Spike Protein (Ser686, N-term) cleaved SARS-CoV-2
Target Alias Names
S, Spike Glycoprotein
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation