Description
Cleaved PARP (Asp214) (D64E10) XP® Rabbit mAb (BSA and Azide Free) detects endogenous levels of the large fragment (89 kDa) of human PARP1 protein produced by caspase cleavage. The antibody does not recognize full-length PARP1 or other PARP isoforms. Mouse cross-reactivity is determined by ELISA. Monoclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp214 in human PARP.
Targets
PARP1 (Asp214, 89 kD) cleaved
Target Alias Name
PARP1
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression