Antibodies under a microscope

Ab04184-3.3

BIBH1 (Sibrotuzumab, huF19)

Description

Recombinant monoclonal antibody to FAP alpha. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody BIBH1 (Sibrotuzumab, huF19). This is a reformatted mouse IgG2b Fc SilentЩ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Target

FAP alpha

Target Alias Names

Seprase, Fibroblast activation protein, Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, FAPalpha, Fibroblast activation protein alpha, Gelatin degradation protease FAP, Integral membrane serine protease, Post-proline cleaving enzyme, Serine integral membrane protease, SIMP, Surface-expressed protease

Isotype/Mimetic

IgG2b

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression