Description
Recombinant monoclonal antibody to VEGFR2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody IMC-1121B (Ramucirumab). This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
Target
VEGFR2
Target Alias Names
Vascular endothelial growth factor receptor 2, kinase insert domain-containing receptor, KDR, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1, CD309, VEGFR-2, Cyramza, LY3009806, 947687-13-0
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression