Description
Recombinant monoclonal antibody to TROP2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody hRS7 (Sacituzumab).
Target
TROP2
Target Alias Names
EGP-1, TACSTD2, GA733-1, M1S1, TROP-2, Tumor-associated calcium signal transducer 2, epithelial glycoprotein-1 antigen, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, IMMU-132, RS7, RS7-3G11
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression