Antibodies under a microscope

Ab04516-10.159

Anti-TLR4 [133-E12], Human IgG1-Fc Fusion,

Description

Recombinant monoclonal antibody to TLR4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody 133-E12. This chimeric human antibody was made using the variable domain sequences of the original Llama VHH format, for improved compatibility with existing reagents, assays and techniques.

Target

TLR4

Target Alias Names

hToll, CD284, Toll-like receptor 4

Isotype/Mimetic

IgG1-Fc Fusion

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression