Description
Recombinant monoclonal antibody to TIGIT. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1B4. This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
TIGIT
Target Alias Names
VSTM3, T cell Ig and ITIM domain, T cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, WUCAM
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression