Description
Recombinant monoclonal antibody to Thrombopoietin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma TN1 . This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
Thrombopoietin
Target Alias Names
C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, TPO
Isotype/Mimetic
Fab fragment
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression