Description
Recombinant monoclonal antibody to Tau. Manufactured using AbAbтАЩs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma MN423. This is a reformatted chimeric human IgG1 Fc SilentтДв antibody made using the variable domain sequences of the original mouse IgG2b format for improved compatibility with existing reagents, assays, and techniques.
Target
Tau
Target Alias Names
MAPT, TAU, PHF-tau, MAPTL, MTBT1, TAU, PHF, Tau proteins, Alzheimer paired helical filaments, Paired helical filament-tau, Microtubule-associated protein tau, Neurofibrillary tangle protein, mAb 423, NOAL 6.423, NOAL 6/66.423.2
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression