Description
Recombinant monoclonal antibody to RANKL. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma IK22-5. This chimeric mouse antibody was made using the variable domain sequences of the original rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Target
RANKL
Target Alias Names
CD254, IK22/5, RANK Ligand, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression