Description
Recombinant monoclonal antibody to PD-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma RMP1-14. This is a bispecific anti-mouse antibody created by fusing anti-CD47 VHH domains to the C-terminus of the heavy chains of the anti-mouse PD1 antibody clone RMP1-14 in a mouse IgG1 D265A format. The mouse IgG1 D265 a format is an Fc-silenced format, preven
Target
PD-1
Target Alias Names
CD279, PD1, PDCD1, RMPI-14, RMP1/14, Programmed Death Receptor 1, Programmed Death 1
Isotypes/Mimetics
Bispecific, anti-mCD47
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression