Antibodies under a microscope

Ab00791-13.12

Anti-PD-1 [5C4.B8 (Nivolumab)], Human IgG4-S228P, kappa

Description

Recombinant monoclonal antibody to PD-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody 5C4.B8 (Nivolumab).

Target

PD-1

Target Alias Names

CD279, programmed death-1, programmed death 1, PD1, PD 1, Programmed cell death protein 1, hPD-1, hPD1, hPD 1, BMS-936558, MDX-1106, ONO-4538

Isotype/Mimetic

IgG4-S228P

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression