Description
Recombinant monoclonal antibody to Pan-Nav1 Na+ channel. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma N419/40. This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Target
Pan-Nav1 Na+ channel
Target Alias Names
N419/40R, Sodium channel protein type 1 subunit alpha, Sodium channel protein brain I subunit alpha, Sodium channel protein type I subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.1, SCN1A
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression