Description
Recombinant monoclonal antibody to PAI-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody MEDI-579. This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Target
PAI-1
Target Alias Names
SERPINE1, PAI1, PAI, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, Humanized Ab167, MEDI579, Antibody 08
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression