Description
Recombinant monoclonal antibody to Nicotinic acetylcholine alpha4 beta 2 receptor. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 12H2. This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
Nicotinic acetylcholine alpha4 beta 2 receptor
Target Alias Names
CHRNB2, Nicotinic acetylcholine α4β2 receptor, Neuronal acetylcholine receptor subunit beta-2, human α4β2 nicotinic receptor, AChR
Isotype/Mimetic
IgM
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression