Description
Recombinant monoclonal antibody to Nav1.1 Na+ channel. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma K74/71. This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
Nav1.1 Na+ channel
Target Alias Names
K74/71R, Voltage-gated sodium channel subunit alpha Nav1.1, Sodium channel protein type 1 subunit alpha, Sodium channel protein brain I subunit alpha, Scn1a, NAC1, SCN1
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression