Description
The antibody is a Mouse IgG2a, kappa targets Mouse BCMA & CD3E
Target
BCMA & CD3E
Target Alias Names
RecName: Full=Tumor necrosis factor receptor superfamily member 17, AltName: Full=B-cell maturation protein, AltName: CD_antigen=CD269, Tnfrsf17, B-cell maturation protein, Tumor necrosis factor receptor superfamily member 17. /id=PRO_0000058936., Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA), as well as TNFRSF13A, cd13414, Extracellular. /evidence=ECO:0000255., CRD1 [structural motif], TNFR-Cys., /evidence=ECO:0000250., CRD2 [structural motif], /evidence=ECO:0000250., /evidence=ECO:0000250., Helical, Signal-anchor for type III membrane protein. /evidence=ECO:0000255., Cytoplasmic. /evidence=ECO:0000255., Missing (in isoform 2). /evidence=ECO:0000303, PubMed:9846698. /id=VSP_006507., T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain. /id=PRO_0000014609., Extracellular. /evidence=ECO:0000255., Ig-like., Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain, pfam16681, /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0000269, PubMed:11439187, ECO:0007744, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., /evidence=ECO:0007829, PDB:1JBJ., Helical. /evidence=ECO:0000255., Cytoplasmic. /evidence=ECO:0000255., /evidence=ECO:0007829, PDB:2K4F., Disordered. /evidence=ECO:0000256, SAM:MobiDB-lite., /evidence=ECO:0007829, PDB:2K4F., NUMB-binding region. /evidence=ECO:0000250, UniProtKB:P07766., ITAM. /evidence=ECO:0000255, PROSITE-ProRule:PRU00379., Proline-rich sequence. /evidence=ECO:0000250, UniProtKB:P07766., Immunoreceptor tyrosine-based activation motif, smart00077, /evidence=ECO:0007829, PDB:2K4F., Phosphotyrosine. /evidence=ECO:0000250, UniProtKB:P07766, ECO:0000255, PROSITE-ProRule:PRU00379., /evidence=ECO:0007829, PDB:2K4F., Phosphotyrosine. /evidence=ECO:0000250, UniProtKB:P07766, ECO:0000255, PROSITE-ProRule:PRU00379., /evidence=ECO:0007829, PDB:2K4F., /evidence=ECO:0007829, PDB:2K4F.
Isotypes/Mimetics
IgG2a, kappa
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
Unknown
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression