Description
Recombinant monoclonal antibody to IL-15. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 146B7 (Ordesekimab; AMG-714). This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
IL-15
Target Alias Names
IL15, Interleukin-15, MGC9721, AMG714, Humax-IL15
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression