Antibodies under a microscope

Ab04653-10.159

Anti-Her2/neu [HerG1M], Human IgG1-Fc Fusion,

Description

Recombinant monoclonal antibody to Her2/neu. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody HerG1M. This reformatted human antibody was made using the variable domain sequences of the original Human VHH format, for improved compatibility with existing reagents, assays and techniques.

Target

Her2/neu

Target Alias Names

CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2

Isotype/Mimetic

IgG1-Fc Fusion

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression