Description
Recombinant monoclonal antibody to H3K4me3. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody 304M3-B. This is a long-neck scFv-Fc fusion protein. The long-neck format allows the two scFvs to bind to the antigen in an "antigen clasping" conformation. For more information please consult Hattori et al. 2016.
Target
H3K4me3
Target Alias Names
trimethyl-Histone H3 (Lys4), histone H3, H3K4, Trimethylated Histone H3, Trimethylated Lys, Trimethylated Lys4, Histone H3 trimethylated at Lysine 4, post translational modification, histone post-translational modification
Isotype/Mimetic
scFv-Fc
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression