Description
Recombinant monoclonal antibody to Fibronectin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody L19 (Radretumab). This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Target
Fibronectin
Target Alias Names
FN, Cold-insoluble globulin, CIG, EDB(+) FN, ED-B domain of fibronectin, Extra domain-B containing fibronectin
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression