Description
Recombinant monoclonal antibody to Collagen type II. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma M2139. This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Target
Collagen type II
Target Alias Names
M2 139, CII, Col II, CollA, ACPA, COL2A1, citrullinated CII, Col C II, citrullinated proteins, antibodies against citrullinated proteins, Collagen alpha-1(II) chain, Alpha-1 type II collagen
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression