Antibodies under a microscope

Ab01486-13.12

Anti-CD22 [LL2 (EPB2)], Human IgG4-S228P, kappa

Description

Recombinant monoclonal antibody to CD22. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma LL2 (EPB2). This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Target

CD22

Target Alias Names

Leu14, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14, EPB2, EPB-2

Isotype/Mimetic

IgG4-S228P

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression