Description
Recombinant monoclonal antibody to Amyloid beta A4 protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody LY2062430 (Solanezumab, hu266). This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
Amyloid beta A4 protein
Target Alias Names
APP, Aβ peptide, Abeta, A-beta, Aβ, Aβ42, amyloid beta peptide, Alzheimer disease amyloid protein, Beta-amyloid precursor protein, Protease nexin-II, humanized m266.2
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression