Description
Recombinant monoclonal antibody to ABCG2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 5D3. This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Target
ABCG2
Target Alias Names
CD338, CDw338, ABCP, BCRP, BCRP1, MXR, Breast cancer resistance protein, mitoxantrone resistance, Urate exporter, Broad substrate specificity ATP-binding cassette transporter ABCG2, ATP-binding cassette sub-family G member 2, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression