Description
Recombinant monoclonal antibody to 4-1BB. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma LOB12.3. This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
4-1BB
Target Alias Names
CD137, TNFRSF9, 41BB, 4-1BBL Ligand, Tumor necrosis factor superfamily member 9, TNF receptor superfamily member 9, LOB 12.3, LOB123, LOB12.3
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression