Description
Recombinant monoclonal antibody to CD30. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma AC10 (Brentuximab). This is a reformatted human IgG1 Fc SilentЩ antibody, based on the original human IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Target
CD30
Target Alias Names
TNFRSF8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, SGN-35, cAC10-Val-Cit-MMAE, ADCETRIS, chimeric AC10, C10
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression