Description
Recombinant monoclonal antibody to EGFRvIII. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 806. This is a reformatted mouse IgG2b Fc SilentЩ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Target
EGFRvIII
Target Alias Names
de2-7 EGFR, ERBB1, ERBB, ErbB-1, Erb-B1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression