Antibodies under a microscope

Ab00282-10.3

7E3 (Abciximab)

Description

Recombinant monoclonal antibody to CD41. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 7E3 (Abciximab). This is a reformatted human IgG1 antibody based on the therapeutic Fab fragment. NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Target

CD41

Target Alias Names

Integrin alpha-IIb, Integrin alpha-2b, ITGA2B, platelet glycoprotein IIb of IIb/IIIa complex

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression