Antibodies under a microscope

Ab00295-2.3

1A8

Description

Recombinant monoclonal antibody to Ly6G. Manufactured using AbAbтАЩs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1A8. This is a murinised antibody to reduce immunogenicity in vivo and was created using our proprietary Fc SilentтДв engineered Fc domain, containing key point mutations that abrogate binding of Fc Receptor and complement.

Target

Ly6G

Target Alias Names

LGR-1, y-6G, GR1, Lymphocyte antigen 6G

Isotype/Mimetic

IgG2a

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression