Description
Recombinant monoclonal antibody to Ly6G. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1A8. This is a murinised antibody to reduce immunogenicity in vivo, however with an isotype chosen to promote depletion of targeted cells via ADCC and CDC
Target
Ly6G
Target Alias Names
LGR-1, y-6G, GR1, Lymphocyte antigen 6G
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression