Antibodies under a microscope

Ab04138-10.3

14F3

Description

Recombinant monoclonal antibody to RANK-L. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 14F3. This is a reformatted human IgG1 Fc SilentЩ antibody, based on the original human IgG2a format, created for improved compatibility with existing reagents, assays and techniques.

Target

RANK-L

Target Alias Names

CD254, TRANCE, RANKL, ODF, OPGL, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression